2008年1月23日 星期三

Galectin-4


Gene map locus 19q13.2


Huflejt et al. (1997) found that LGALS4 is expressed as a 38-kD protein in the human colon adenocarcinoma T84 cell line.In confluent T84 cells, LGALS4 is mainly cytosolic and is concentrated at the basal membrane. In subconfluent T84 cells, it is found in attachment sites of newly seeded cells and is concentrated at the leading edge of lamellipodia. Based on the localization of LGALS4 and the ability of immobilized recombinant rat Lgals4 to enhance adhesion of T84 cells, Huflejt et al. (1997) suggested that LGALS4 plays a role in cell adhesion.


GenBank: NM_006149


Protein : EAW56820


Reference:
http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602518


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